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Type I and type II pathways of Fas-mediated apoptosis are differentially controlled by XIAP Free
Zhenyue Hao * and Tak W. Mak*
The Campbell Family Cancer Research Institute, University Health Network, Toronto, ON, Canada *Correspondence to:Zhenyue Hao, E-mail: zyhao@uhnres.utoronto.ca; Tak W. Mak, E-mail: tmak@uhnres.utoronto.ca
J Mol Cell Biol, Volume 2, Issue 2, April 2010, 63-64,  https://doi.org/10.1093/jmcb/mjp034

The mechanism by which Fas activates the apoptotic pathway differs in so-called type I and type II cells. X chromosome-linked inhibitor of apoptosis protein has now been revealed as an important molecule that is differentially regulated in type I vs. type II cells.

Volume 2, Issue 2
April 2010